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mid-dermal elastolysis
Etiology:
- idiopathic
- reported associations
- ultraviolet radiation exposure
- pregnancy
- oral contraceptive use
- dermatitis
- autoimmune diseases
Epidemiology:
- rare
- female Caucasians
Pathology:
- may appear normal or with inflammatory infiltrate on H&E stain
- focal loss of elastic fiber may be seen
Clinical manifestations:
- distribution:
- trunk & upper arms most common
- face & lower legs are only occasionally affected
- type 1: (most common)
- asymptomatic, well-demarcated areas of fine wrinkling
- type 2:
- looseness of skin around hair follicles, resulting in perifollicular papules
- type 3: reticular erythema
* images [1]
Management:
- sunscreen
- topical retinoids
General
cutis laxa; elastolysis; loose skin; pachydermatocele
References
- Chan B
Mid-dermal elastolysis
DermNet New Zealand
https://www.dermnetnz.org/topics/mid-dermal-elastolysis