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methylmalonate; methylmalonic acid (MMA)

In man it is involved in the degradation of several amino acids, odd-chain fatty acids & cholesterol via propionyl-CoA to the tricarboxylic acid cycle. Metabolism of methylmalonate is dependent upon adenosylcobalamin (vitamin B12).

Related

malonyl-CoA-acyl carrier protein transacylase, mitochondrial; MCT; mitochondrial malonyltransferase; [acyl-carrier-protein] malonyltransferase (MCAT, MT) methylmalonate in serum methylmalonic acidemia/aciduria methylmalonyl Coenzyme A mutase; succinyl CoA mutase; methylmalonyl CoA isomerase (MUT, MCM)

General

malonate; malonic acid

Database Correlations

PUBCHEM correlations

References

  1. PROSITE :accession PS00544
  2. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998