methaqualone (Quaalude, Mozambin)

Tradename: Quaalude. Laboratory: 1) specimen: serum, plasma (heparin, EDTA) 2) methods: GLC, MS, HPLC, color 3) interferences: -> chlordiazepoxide & diazepam may interfere with color method 4) labs with Loincs - methaqualone in specimen - methaqualone in hair - methaqualone in body fluid - methaqualone in vitreous fluid - methaqualone in gastric fluid - methaqualone in bile - methaqualone in meconium - methaqualone in stool - methaqualone in serum/plasma - methaqualone in urine Mechanism of action: Sedative? with abuse potential.

Properties

MISC-INFO: elimination route LIVER 1/2life 10-42 HOURS therapeutic-range 2-3 UG/ML toxic-range >10 UG/ML protein-binding 70-90% elimination by hemodialysis - hemoperfusion + peritoneal dialysis -

References

Clinical Guide to Laboratory Tests, 3rd edition, NW Tietz ed, WB Saunders, Philadelphia, 1995