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meningoccal conjugate vaccine ACWY (Menveo)
different vaccines for different serotypes
Indications:
- prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, Y, and W-135
- routine use in adolescents age 11- 12 years, with a booster at 16 years
- immunosuppressed* persons age 2-54 years
- 1st dose administered after age 16 years a booster is not required
- college freshmen living in resident halls should receive the vaccine within 5 years of enrollment
- all patients with HIV1 disease
- 2 dose schedule for patients > 2 years of age plus booster doses every 5 years [4]
* patients with terminal complement deficiency are at higher risk for meningococcal disease
- patients with immunoglobulin deficiency are not [2]
Notes:
- sometimes improperly prepared and administered by providers [1]
Related
Neisseria meningitidis (meningococcus)
Specific
meningococcal polysaccharide vaccine (Menomune-A/C/Y/W-135, MenACWY-CRM, Menactra, MenACYW-D)
General
meningococcal vaccine
References
- Su JR, Miller ER, Duffy J et al
Notes from the Field: Administration Error Involving a
Meningococcal Conjugate Vaccine- United States, March 1, 2010-
September 22, 2015.
MMWR Weekly / February 19, 2016 / 65(6);161-162
http://www.cdc.gov/mmwr/volumes/65/wr/mm6506a4.htm
- Medical Knowledge Self Assessment Program (MKSAP) 17,
American College of Physicians, Philadelphia 2015
- Cohn AC, MacNeil JR, Clark TA et al for the Centers for Disease
Control and Prevention (CDC).
Prevention and control of meningococcal disease: recommendations
of the Advisory Committee on Immunization Practices (ACIP).
MMWR Recomm Rep. 2013 Mar 22;62(RR-2):1-28.
PMID: 23515099 Free Article
- MacNeil JR, Rubin LG, Patton M, Ortega-Sanchez IR, Martin SW.
Recommendations for Use of Meningococcal Conjugate Vaccines in
HIV-Infected Persons - Advisory Committee on Immunization
Practices, 2016.
MMWR Morb Mortal Wkly Rep 2016;65:1189-1194
https://www.cdc.gov/mmwr/volumes/65/wr/mm6543a3.htm
Component-of
Haemophilus b Conjugate Vaccine - Meningococcal Protein Conjugate (Hib-MenCY-TT)
haemophilus b conjugate vaccine meningococcal protein conjugate