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boutonneuse fever; Mediterranean spotted fever

Etiology: Rickettsia conorrii Epidemiology: 1) endemic in Mediterranean, India, Africa 2) transmitted by ticks 3) reservoir: rodents, dogs 4) spring, summer Clinical manifestations: 1) incubation period 2-14 days 2) fever, headaches, myalgias 3) maculopapular skin eruption (rarely vesicular & petechial) - generally begins on ankles & wrists - involves palms & soles [3] 4) eschar at site of tick bite 5) eruption on proximal extremities, spreading to face & trunk 6) regional adenopathy Laboratory: - Rickettsia DNA Complications: - neurologic manifestations Management: - see Rocky Mountain spotted fever (doxycycline for 7-10 days)

Related

eschar familial Mediterranean fever (FMF, recurrent polyserositis) Rickettsia conorrii

General

rickettsial spotted fever; tick typhus

References

  1. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 91
  2. Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 748
  3. Medical Knowledge Self Assessment Program (MKSAP) 18, American College of Physicians, Philadelphia 2018