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methyl-CpG-binding protein 1 (MECP-1)
MECP-1 represses gene transcription by binding to methylated CpG islands. Binding requires methylation of several CpG dinucleotides.
Related
DNA methylation (promoter methylation)
General
methyl-CpG-binding protein (MECP, Me-CpG-BP)
Properties
COMPARTMENT: cell nucleus
MOTIF: DNA-binding motif
binding site
FOR-BINDING-OF: histone deacetylase
Database Correlations
OMIM 300005
MORBIDMAP 300005
References
Genes VII, Lewis B., Oxford University Press, NY, 2000