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measles virus (rubeola)

Humans are the only natural host. Epidemiology: - infectious virus remained detectable on stainless steel surfaces for as long as 3 days Laboratory: - measles virus serology - measles virus RNA - measles virus N gene - measles virus identified by culture - see ARUP consult [1] Management: - mouthwash, hand sanitizers, & surface agents all eradicated measles virus in vitro [2] - 4 of 7 mouthwashes tested (including 2 Listerine products widely available in the U.S.) eliminated detectable virus after a 30-second exposure - hand sanitizers inactivated virus after 30-second exposures - 4 commercially available alcohol- & aldehyde-based disinfectants eliminated stainless steel surface virus after 30 seconds to 5 minute exposures [2] - an H2O2-based product reduced but did not eliminate surface virus[2]

Related

measles (1st disease)

Specific

SSPE measles virus

General

paramyxoviridae

Properties

KINGDOM: virus GENOME-TYPE: RNA SINGLE-STRANDED NEGATIVE-STRAND GENOME-SIZE: 16-20 kB ENVELOPE: PRESENT CAPSID-SYMMETRY: HELICAL

References

  1. ARUP Consult: Measles Virus - Rubeola The Physician's Guide to Laboratory Test Selection & Interpretation https://www.arupconsult.com/content/measles-virus
  2. Sandoval Flores LD, Addo MM, Steinmann E, Meister TL. Susceptibility of Measles Virus to World Health Organization-Recommended Hand Rubs, Oral Rinses, and Surface Disinfectants. Open Forum Infect Dis. 2025 Oct 14;12(11):ofaf627. PMID: 41180003 PMCID: PMC12575076 Free PMC article. https://pmc.ncbi.nlm.nih.gov/articles/PMC12575076/