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myoD family inhibitor (myogenic repressor I-mf, MDFI)
Function:
1) inhibits transactivation of the Myod family of myogenic factors
2) represses myogenesis
3) associates with Myod family members & retains them in the cytoplasm by masking their nuclear localization signals
4) interferes with DNA-binding activity of Myod family members
5) trophoblast and chondrogenic differentiation
Compartment: cytoplasm
General
other protein
Properties
SIZE: MW = 25 kD
entity length = 246 aa
COMPARTMENT: cytoplasm
MOTIF: cysteine-rich region {163-243}
Database Correlations
OMIM 604971
UniProt Q99750
References
UniProt :accession Q99750