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DNA replication licensing factor MCM5; CDC46 homolog; P1-CDC46 (MCM5, CDC46)

Function: - CDC46 forms a stable complex with P1Mcm3 Structure: - belongs to the MCM family - contains 1 MCM domain Compartment: nucleus

General

minichromosome maintenance (Mcm) protein

Properties

SIZE: entity length = 734 aa MW = 82 kD COMPARTMENT: cell nucleus MOTIF: MCM {331-537} MOTIF: ATP-binding site NAME: ATP-binding site SITE: 381-388

Database Correlations

OMIM 602696 UniProt P33992 Pfam PF00493 Entrez Gene 4174 Kegg hsa:4174

References

  1. UniProt :accession P33992
  2. Musahl C et al A human homologue of the yeast replication protein Cdc21. Interactions with other Mcm proteins. Eur J Biochem 230:1096 1995 PMID: 7601140
  3. NIEHS-SNPs http://egp.gs.washington.edu/data/mcm5/

Component-of

minichromosome maintenance (Mcm) complex