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MAP kinase activity (GO:0004707)
Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
Related
mitogen-activated protein kinase 3 (ERK1, ERT2, p44mapk, p44erk1, insulin-stimulated MAP2 kinase, myelin basic protein [MBP] kinase E4, RSK kinase-2, MAPK3, PRKM3)
Specific
MAP kinase activity involved in cell wall organization or biogenesis (GO:0038067)
MAP kinase activity involved in conjugation with cellular fusion (GO:0038071)
MAP kinase activity involved in innate immune response (GO:0038075)
MAP kinase activity involved in osmosensory signaling pathway (GO:0038079)
SAP kinase activity (GO:0016909)
General
receptor signaling protein serine/threonine kinase activity (GO:0004702)
References
gene ontology: GO:0004707