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malar rash (butterfly rash)

Butterfly shaped rash on face (maxillary nerve distribution) Etiology: - 46-65% of patients with systemic lupus erythematosus Clinical manifestations: - red or purplish & mildly scaly rash - shape of a butterfly - involves the bridge of the nose - spares the nasolabial folds of the face & areas beneath the nose & lower lip * images [3] Laboratory: - antinuclear antibody (ANA) & further testing for systemic lupus erythematosus if positive Differential diagnosis: - disorders not sparing nasolabial folds - rosacea (facial flushing that flares with strong emotion, hot drinks) - dermatomyositis (heliotrope rash, Grotton's papules) - erythema infectiosum due to parvovirus B19 infection (slapped cheek rash) - erysipelas may spare nasolabial folds - sharply demarcated erythema may be at the border of the nasolabial folds - fever, chills, malaise, male

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rash

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 14, American College of Physicians, Philadelphia 2006
  2. Wikipedia: Malar rash http://en.wikipedia.org/wiki/Malar_rash
  3. Goglin SE, Margaretten ME Images in Clinical Medicine: Malar Rash N Engl J Med 2021; 385:164. July 8 PMID: 34233099 https://www.nejm.org/doi/full/10.1056/NEJMicm2029589