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major depression with psychosis; psychotic/delusional depression
Etiology:
- may be manifestation of major depression following stroke
- may occur in patients with illness anxiety disorder
Clinical manifestations:
- combination of depression & psychosis
- psychosis often manifests as belief bad things are going to happen
Management:
- treatment with both antidepressant & antipsychotic if early in the course of disease
- hospitalize for electroconvulsive therapy if resistant depression, or urgency due to rapid deterioration (substantial weight loss, frailty, agitation)
General
major depression
psychosis
References
- Rothchild AJ
Challenges in treatment of major depressive disorder with psychotic features.
Schizophr Bull.2103;39(4):787-796
PMID: 23599251 PMCID: PMC3686458 Free PMC article