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magnesium citrate (citrate of magnesia)

Indications: - relief of constipation - hypomagnesemia - dyspepsia - bowel preparation Contraindications: pregnancy-category :value + safety-in-lactation :value ? Dosage: 1) 4 mL/kg PO up to 300 mL [1] 2) 4-8 oz once; may be repeated once [2] Liquid: 10 oz bottle. Pharmacokinetics: 1) onset of bowel relief is in 3-6 hours 2) elimination :route kidney) Adverse effects: - repeated or frequent administration may cause a) hypermagnesemia b) electrolyte imbalance c) dehydration Mechanism of action: 1) saline laxative 2) Mg+2 may stimulate release of cholecystokinin, which increases motor & sensory action in the GI tract

Related

calcium & magnesium citrate

General

pharmaceutical magnesium laxative citrate (citric acid)

Database Correlations

PUBCHEM correlations

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. Deprecated Reference

Component-of

calcium & magnesium citrate calcium lactate/glucose/magnesium citrate/potassium chloride/sodium chloride dimethicone/magnesium citrate magnesium citrate/simethicone