measles & rubella combined vaccine (M-R-VAX II)

Indications: 1) simultaneous immunization against measles & rubella 2) measles-mumps-rubella vaccine (MMR) is the preferred vaccine for most children & many adults Contraindications: 1) immunodeficiency 2) pregnancy Dosage: Children > 15 months & adults: 0.5 mL SC Injection: 1000 TCID50 each of: 1) live attenuated measles virus vaccine 2) live rubella vaccine Adverse effects: 1) common (> 10%) - fever < 100 F - burning at site of injection - arthralgias - local tenderness & erythema - urticaria - rash 2) less common (1-10%) - fever 100-103 F, delayed-type allergic reaction, malaise, headache, sore throat, lymphadenopathy 3) uncommon (< 1%) - difficulty breathing, hives, itching, reddening of skin (especially around eyes & ears), tiredness, convulsions, encephalitis, confusion, severe headache, stiff neck, vomiting, diplopia, thrombocytopenic purpura, prolonged fever > 103 F, optic neuritis, hypersensitivity * Also see individual components:

Related

measles virus vaccine, live, attenuated (Attenuvax) measles, mumps & rubella combined vaccine (MMR) rubella virus vaccine, live (Meruvax II)

References

Kaiser Permanente Northern California Regional Drug Formulary, 1998