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lymph node metastases

Etiology: - breast cancer(60-80%) - lung cancer (83% local, 29% distant) - prostate cancer (68%) - melanoma (58%) - ovarian cancer (48% local, 58% distant) - colorectal carcinoma (53%) Laboratory: - lymph node metastatic deposit.max dimension in cancer specimen - lymph node response to neoadjuvant therapy in cancer specimen - lymph node site of origin in cancer specimen - lymph nodes with isolated tumor cells in cancer specimen - lymph nodes with macrometastases in cancer specimen - lymph nodes with micrometastases in cancer specimen Special laboratory: - some artificial intelligence computer programs can outperform pathologists in detecting lymph node metastases of breast cancer - top-performing programs all used deep learning-based systems that utilized AI to extract meaningful patterns [1] - AI may be more accurate than the pathologists with a time constraint & comparable to pathologists with no time limit [1] Notes: - see metastasis

Specific

secondary malignant neoplasm of lymph nodes

General

metastasis

References

  1. Bejnordi BE, Veta M, van Diest PJ et al Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer. JAMA. 2017;318(22):2199-2210 PMID: 29234806 https://jamanetwork.com/journals/jama/article-abstract/2665774 - Golden JA. Deep Learning Algorithms for Detection of Lymph Node Metastases From Breast Cancer. Helping Artificial Intelligence Be Seen. JAMA. 2017;318(22):2184-2186 PMID: 29234791 https://jamanetwork.com/journals/jama/article-abstract/2665757