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lung neoplasm
WHO classification of Pulmonary Neoplasms
Malignant epithelial tumors
1) squamous cell carcinoma
a) papillary
b) clear cell
c) small cell
d) basaloid
2) small cell carcinoma
- combined small cell carcinoma
3) adenocarcinoma
a) adenocarcinoma, mixed subtype
b) acinar adenocarcinoma
c) papillary adenocarcinoma
d) bronchioloalveolar carcinoma
1] nonmucinous
2] mucinous
3] mixed mucinous & nonmucinous or indeterminate
e) solid adenocarcinoma with mucin production
1] fetal adenocarcinoma
2] mucinous ("colloid") carcinoma
3] mucinous cystadenocarcinoma
4] signet ring adenocarcinoma
5] clear cell adenocarcinoma
4) large cell carcinoma
a) large cell neuroendocrine carcinoma
- combined large cell neuroendocrine carcinoma
b) basaloid carcinoma
c) lymphoepithelioma-like carcinoma
d) clear cell carcinoma
e) large cell carcinoma with rhabdoid phenotype
5) adenosquamous carcinoma
6) sarcomatoid carcinoma
a) pleomorphic carcinoma
b) spindle cell carcinoma
c) giant cell carcinoma
d) carcinosarcoma
e) pulmonary blastoma
7) carcinoid tumor
a) typical carcinoid
b) atypical carcinoid
8) salivary gland tumors
a) adenoid cystic carcinoma
b) mucoepidermoid carcinoma
c) epithelial-myoepithelial carcinoma
9) pre-invasive lesions
a) squamous carcinoma in situ
b) atypical adenomatous hyperplasia
c) diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
10) mesenchymal tumors
a) epithelioid hemangioendothelioma
b) angiosarcoma
c) pleuropulmonary blastoma
d) chondroma
e) congenital peribronchial myofibroblastic tumor
f) diffuse pulmonary lymphangiomatosis
g) inflammatory myofibroblastic tumor
h) lymphangioleiomyomatosis
i) synovial sarcoma
1] monophasic
2] biphasic
j) pulmonary artery sarcoma
k) pulmonary vein sarcoma
Benign epithelial tumors
1) papillomas
a) squamous cell papilloma
1] exophytic
2] inverted
b) glandular papilloma
c) mixed squamous cell and glandular papilloma
2) adenomas
a) alveolar adenoma
b) papillary adenoma
c) adenomas of salivary gland type
1] mucous gland adenoma
2] pleomorphic adenoma
3] other
d) mucinous cystadenoma
3) lymphoproliferative tumors
a) marginal zone B-cell lymphoma of MALT type
b) diffuse large B-cell lymphoma
c) lymphomatoid granulomatosis
d) Langerhans cell histiocytosis
Miscellaneous tumors
1) hamartoma
2) sclerosing hemangioma
3) clear cell tumor
4) germ cell tumor
a) teratoma, mature
b) teratoma, immature
c) other
5) intrapulmonary thymoma
6) melanoma
Metastatic tumors
Specific
benign lung neoplasm
bronchial carcinoid
lung cancer
pleural neoplasm
General
lung disease
respiratory tract neoplasm
References
WHO Classification Tumours of the Lung, Pleura, Thymus and Heart.
Travis et al., ed. IARC Press 2004