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lumbosacral radiculoplexus neuropathy
Etiology:
- diabetic amyotrophy (2/3)
Epidemiology:
- 4 cases per 100,000 population
Pathology:
- microvasculitis with ischemic nerve injury involving the lumbosacral plexus & nerve roots
Clinical manifestations:
- acute or subacute painful neuropathy
- painful lower-extremity presentations & muscle weakness
- a few cases sensory-predominant
- generally unilateral: asymmetric when bilateral
- generally proximal > distal (sometimes both)
- cervical or thoracic involvement also may occur
Specific
diabetic amyotrophy/lumbar polyradiculopathy; diabetic lumbosacral radiculoplexus neuropathy (DLRPN)
General
sciatica; lumbosacral radiculopathy; sciatic neuropathy
lumbosacral plexopathy
References
- Ng PS, Dyck PJ, Laughlin RS, Thapa P, Pinto MV, Dyck PJB.
Lumbosacral radiculoplexus neuropathy:
Incidence and the association with diabetes mellitus.
Neurology 2019 Mar 12; 92:e1188.
PMID: 30760636
https://n.neurology.org/content/92/11/e1188