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lodoxamide (Alomide)

Tradenames: Alomide. Indications: - treatment of vernal keratoconjunctivitis, vernal conjunctivitis, & vernal keratitis Contraindications: Caution: NOT for use in patients wearing soft contact lenses Dosage: - adults & children > 2 years of age: - 1-2 drops QID for up to 3 months Solution: 0.1% (10 mL) Adverse effects: 1) common (> 10%) - transient burning, stinging, discomfort 2) less common (1-10%) - blurred vision, corneal erosion/ulcer, eye pain, corneal abrasion, headache 3) uncommon (< 1%) - dizziness, somnolence, rash, nausea, stomach discomfort, blepharitis, sneezing, dry nose 4) other - crystalline deposits Mechanism of action: - mast-cell stabilizer that inhibits type-1 immediate hypersentivity reaction

General

ocular decongestant

Properties

MISC-INFO: elimination route KIDNEY pregnancy-category B safety in lactation ?

Database Correlations

PUBCHEM cid=44563

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998