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lissencephaly type 3

Pathology: - agyria or pachygyria or laminar heterotopia - abnormalities of corpus callosum, hippocampus, cerebellar vermis & brainstem Genetics: - associated with defects in TUBA1A Clinical manifestations: - severe mental retardation - motor delay - variable presence of seizures

General

lissencephaly; agyria

References

OMIM :accession 257320