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Lisch nodule
pigmented hamartomatous nevus affecting the iris, named after Austrian ophthalmologist Karl Lisch (1907-1999), who described them in 1937
Etiology:
- found in patients with neurofibromatosis type 1
Pathology:
- clear, yellow-brown, oval to round, dome-shaped papules that project from the surface of the iris
- nodules generally do not affect vision
- nodules stain positive for vimentin & S-100
- likely of ectodermal origin
Special laboratory:
- nodules etected by slit lamp examination
General
nodule
References
- Wikipedia: Lisch nodule
http://en.wikipedia.org/wiki/Lisch_nodule
- Lisch nodule images
http://images.google.com/images?hl=en&source=hp&q=Lisch+nodule&rlz=1R2GFRE_en&um=1&ie=UTF-8&ei=wecfS8vqMIeqtgOfzZz_CQ&sa=X&oi=image_result_group&ct=title&resnum=4&ved=0CB4QsAQwAw