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lipoma; adipocyte neoplasm

Single or multiple, benign subcutaneous tumors of adipose tissue. Pathology: 1) normal appearing adipocytes 2) may be connective tissue framework * gross pathology image [4] Clinical manifestations: 1) soft, rounded or lobulated subcutaneous masses movable against the overlying skin 2) size small to 12 cm 3) distribution: head & neck, trunk & extremities * images [5] Laboratory: - skin biopsy not necessary [3] Complications: - constipation (case report) [2] Differential diagnosis: - epidermoid cyst - firmer, less compressible than lipoma - may have central punctum & drain rancid keratin debris Management: 1) surgical excision early: small lipomas are much easier to excise than large ones

Related

adipositas dolorosa; Dercum's disease; Anders disease; fatty tissue rheumatism; lipomatosis dolorosa morbus dercum's benign symmetric lipomatosis (Madelung disease) familial lipoma syndrome

Specific

lipoblastoma lipofibroma lipomyelomeningocele

General

adipose tissue neoplasm benign neoplasm

References

  1. Color Atlas and Synopsis of Clinical Dermatology, Common and Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY, 1997, pg 178
  2. Hardy CL, Goliath G Constipation Associated with a Lipoma. N Engl J Med 2015; 373:656. August 13, 2015 PMID: 26267625 http://www.nejm.org/doi/full/10.1056/NEJMicm1413283
  3. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015
  4. Nickloes TA, Geibel J (gross pathology, radiology images) Medscape: Lipomas http://emedicine.medscape.com/article/191233-overview
  5. DermNet NZ. Lipoma and liposarcoma (images) http://www.dermnetnz.org/lesions/lipoma.html
  6. Dalal KM, Antonescu CR, Singer S. Diagnosis and management of lipomatous tumors. J Surg Oncol. 2008 Mar 15;97(4):298-313. PMID: 18286473 Review.