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lipofuscin
Yellow-brown, finely granular intracytoplasmic pigment, particularly prominent in liver & heart of aging patients. Represents indigestible residue of autophagocytic vesicles. Composed of polymers of lipids & phospholipids complexed with protein.
Related
N-retinylidine-N-retinyl ethanolamine
neuronal ceroid lipofuscinosis
Specific
retinal pigment epithelium lipofuscin
General
abnormal morphologic structure (malformation)
lipid
pigment
References
- Cotran et al, Robbins Pathologic Basis of Disease,
W.B. Saunders Co, Philadelphia, PA 1989 pg 24
- Harman, Lipofuscin & Ceroid Pigments, EA Porta (ed),
Plenum Press, NY, 1990, pg 3