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Li+ in serum/plasma
Indications:
- therapeutic drug monitoring, lithium carbonate therapy
- bipolar affective disorder
Reference interval:
- therapeutic range: 0.5-1.4 mmol/L
Clinical significance:
- relatively narrow therapeutic range
- see lithium carbonate for toxicity
Increases:
- lithium toxicity
Specimen:
- see Li+ in serum/plasma/blood
Methods:
- flame emission spectroscopy (FES)
- atomic absorption spectroscopy (AAS)
- ion-specific electrode (ISE)
Interferences:
- Na+, K+ & Ca+2 may interfere with flame emission method & require background correction
Related
Li+
lithium carbonate (Eskalith, Lithane, Lithobid, Lithonate)
pharmaceutical lithium
General
Li+ in serum/plasma/blood
References
- Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,
W.B. Saunders, 1995
- Lithium, Serum or Plasma
Laboratory Test Directory ARUP: 20038