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Li+ in blood

Indications: - therapeutic drug monitoring, lithium carbonate therapy - bipolar affective disorder Reference interval: - therapeutic range: 0.5-1.4 mmol/L Clinical significance: - relatively narrow therapeutic range - see lithium carbonate for toxicity Increases: - lithium toxicity Specimen: - see Li+ in serum/plasma/blood Methods: - flame emission spectroscopy (FES) - atomic absorption spectroscopy (AAS) - ion-specific electrode (ISE) Interferences: - Na+, K+ & Ca+2 may interfere with flame emission method & require background correction

Related

Li+ lithium carbonate (Eskalith, Lithane, Lithobid, Lithonate) pharmaceutical lithium

General

lithium measurement therapeutic drug measurement

References

  1. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  2. Lithium, Serum or Plasma Laboratory Test Directory ARUP: 20038