Search
leukotriene D
Together with leukotriene-C & E = SRS-A (slow-reacting substance of anaphylaxis). Promotes smooth muscle contraction of pulmonary airways, trachea & intestines, & increases permeability of microvasculature. [For molecular structure, see specific subtype in arachidonate or eicosapentaenoate cascade.]
Related
lipoxygenase cascade
Specific
leukotriene D4
leukotriene D5
General
leukotriene
Properties
COMPARTMENT: membrane
SECRETED-BY: neutrophil
macrophage
mast cell
References
Textbook of Biochemistry with Clinical Correlations,
3rd ed., TM Devlin (ed), Wiley-Liss, NY 1992 pg 469