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leukocytes in pericardial fluid

Clinical significance: - 2000/uL not indicative of autoimmune pericarditis - lymphocyte predominance suggests consideration of tuberculosis Management: - colchicine +/- NSAID for treatment & prevention of pericarditis [1,2,3,4]

Related

leukocyte (white blood cell) pericardial fluid

Specific

Leukocytes other in pericardial fluid lymphocytes in pericardial fluid mononuclear cells in pericardial fluid

General

leukocytes (WBC) in body fluid

References

  1. Imazio M, Bobbio M, Cecchi E, Demarie D, Pomari F, Moratti M, Ghisio A, Belli R, Trinchero R. Colchicine as first-choice therapy for recurrent pericarditis: results of the CORE (COlchicine for REcurrent pericarditis) trial. Arch Intern Med. 2005 Sep 26;165(17):1987-91. PMID: 16186468 - Imazio M, Cecchi E, Ierna S et al Investigation on Colchicine for Acute Pericarditis: a multicenter randomized placebo-controlled trial evaluating the clinical benefits of colchicine as adjunct to conventional therapy in the treatment and prevention of pericarditis; study design amd rationale. J Cardiovasc Med (Hagerstown). 2007 Aug;8(8):613-7. PMID: 17667033
  2. Medical Knowledge Self Assessment Program (MKSAP) 16, 18 American College of Physicians, Philadelphia 2012, 2018.
  3. Imazio M et al. for the ICAP Investigators. A randomized trial of colchicine for acute pericarditis. N Engl J Med 2013 Sep 1 PMID: 23992557 http://www.nejm.org/doi/full/10.1056/NEJMoa1208536
  4. Meyer BJ Mounting Evidence Supports Colchicine for Pericarditis. NEJM Journal Watch. May 19, 2014 Massachusetts Medical Society (subscription needed) http://www.jwatch.org - Imazio M et al. Efficacy and safety of colchicine for treatment of multiple recurrences of pericarditis (CORP-2): A multicentre, double- blind, placebo-controlled, randomised trial. Lancet 2014 Mar 30; PMID: 24694983 - Cacoub PP. Colchicine for treatment of acute or recurrent pericarditis. Lancet 2014 Mar 30 PMID: 24694984