leucine zipper tumor suppressor 2 (protein LAPSER1, LZTS2, KIAA1813, LAPSER1)

Function: - may act as tumor suppressor - overexpression inhibits growth & colony-forming efficiency of many cancer cell lines Structure: belongs to the LZTS family Expression: - highly expressed in prostate & testis, & at slightly lower levels in spleen, thymus, uterus, small intestine & colon

General

anti-oncoprotein (tumor suppressor protein) other protein

Properties

SIZE: MW = 73 kD entity length = 669 aa MOTIF: serine-rich region {188-197} MOTIF: serine residue (SEVERAL) proline-rich region SITE: 312-319 MOTIF: proline residue (SEVERAL) coiled coil {328-656}

Database Correlations

UniProt Q9BRK4 Pfam PF06818

References

UniProt :accession Q9BRK4