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lentigo; melanocytic macule

A brown macule resembling a freckle. Etiology: - multiple mucosal lentigenes associated with - Peutz-Jeghers syndrome - Laugier-Hunziker syndrome - idiopathic Pathology: 1) proliferation of the rete ridges 2) scattered melanocytes (increased numbers) are seen in the basal cell layer 3) increased pigment occur in the epidermis Clinical manifestations: 1) 0.3-1.5 cm macule 2) tan to black in color 3) distribution a) most commonly in sun-exposed areas b) face, lower lip, upper trunk, extremities 4) borders are generally regular * images [4] Management: 1) observation 2) cryosurgery 3) lasers that target melanin

Related

dermal melanocytic nevus (basal cell nevus)

Specific

lentigo maligna lentigo simplex melanotic macule; labial lentigo solar (senile) lentigo

General

skin neoplasm

References

  1. Color Atlas and Synopsis of Clinical Dermatology, Common and Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY, 1997, pg 144, 181, 192-194, 232, 235-237, 304-305
  2. Stedman's Medical Dictionary 26th ed, Williams & Wilkins, Baltimore, 1995
  3. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 319
  4. DermNet NZ. Lentigo (images) http://www.dermnetnz.org/lesions/lentigines.html