LCCL domain

Named for proteins found to contain it: - Limulus factor C - cochlin - late gestation lung protein Lgl1 Domain of about 100 amino acid residues domain with C-terminal region that contains a conserved histidine in a conserved motif YxxxSxxCxAAVHxGVI. It is an autonomously folding domain used for the construction of modular proteins through exon-shuffling. It may be involved in lipopolysaccharide (LPS) binding. The LCCL domain is found in association with: - complement B-type domains - C-type lectin domains - von Willebrand type A domains - CUB domains - discoidin lectin domains - CAP domains Secondary structure prediction suggests that the LCCL domain contains 6 beta strands & 2 alpha helices

References

prosite :accession PS50812