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LanC-like protein 2 (testis-specific adriamycin sensitivity protein, LANCL2, GPR69B, TASP)
Structure: belongs to the LanC-like protein family
Compartment: nucleus, cytoplasm, cell membrane
Expression: expressed in brain & testis
Pathology:
- bystander coamplified & overexpressed with epidermal growth factor receptor (EGFR) in 20% of all glioblastomas
- exogenous expression in a sarcoma cell line decreases the expression of ABCB1 (P-glycoprotein 1) & increases cellular sensitivity to an anticancer drug adriamycin
General
LanC-like protein; lanthionine-synthetase component C-like 1 (LanC-LIKE, LANCL)
Properties
SIZE: MW = 51 kD
entity length = 450 aa
COMPARTMENT: cytoplasm
cell nucleus
Database Correlations
UniProt Q9NS86
Pfam PF05147
References
UniProt :accession Q9NS86