laminin

Function: - binds to cells via a high affinity receptor - mediates the attachment, migration & organization of cells into tissues during embryonic development by interacting with other extracellular matrix components Structure: - complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long & three short arms with globules at each end

Specific

laminin-1 (EHS laminin) laminin-12 laminin-2 (merosin) laminin-3 (S-laminin) laminin-4 (S-merosin) laminin-5 laminin-6 (K-laminin) laminin-7 (KS-laminin)

General

cell adhesion protein glycoprotein matrix protein multisubunit protein

Properties

COMPARTMENT: extracellular matrix MOTIF: glycosylation site focal adhesion site SUBUNITS: laminin-alpha laminin-beta laminin-gamma

Components

laminin-alpha (laminin A) laminin-beta (laminin B1) laminin-gamma (laminin B2)