kinesin light chain 3 (KLC3, KLC2-like, KLC2L)

Function: 1) kinesin light chain 2) interacts with KIF5C & ODF1 3) heptad repeat motif interacts with kinesin heavy chains & ODF1 4) TPR region is involved in mitochondrial binding Elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) associates with mitochondria Alternative splicing: named isoforms=3

General

kinesin family protein kinesin light (beta) chain mitochondrial protein

Properties

SIZE: MW = 70 kD entity length = 504 aa COMPARTMENT: mitochondria MOTIF: coiled coil {90-150} glutamate-rich region {181-184} MOTIF: glutamate residue (SEVERAL) alanine-rich region {190-196} MOTIF: alanine residue (SEVERAL) tetratricopeptide repeat {207-240} binding site FOR-BINDING-OF: protein tetratricopeptide repeat {249-282} tetratricopeptide repeat {291-324} tetratricopeptide repeat {333-366} tetratricopeptide repeat {375-408}

Database Correlations

OMIM 601334 UniProt Q6P597 PFAM correlations

References

OMIM :accession Q6P597