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kinesin
Function:
- kinesin directs plus-end or anterograde movement of vesicles along microtubules, whereas cytoplasmic dynein directs minus-end or retrograde transport
Related
kinesin family protein
Specific
kinesin-1
kinesin-2
General
adenosine triphosphatase (ATPase)
guanosine triphosphatase (GTPase)
microtubule-associated protein (MAP)
multisubunit protein
Properties
COMPARTMENT: cytoplasm
MOTIF: active site
MOTIF: adenine nucleotide-binding site
guanine nucleotide-binding site
SUBUNITS: kinesin heavy (alpha) chain (2)
MOTIF: active site
SITE: N-TERMINAL
MOTIF: P-loop {N-TERMINAL}
FOR-BINDING-OF: adenosine triphosphate
binding site
FOR-BINDING-OF: microtubule
domain
MOTIF: alpha helix
coiled coil
binding site
SITE: C-TERMINAL
EFFECTOR-BOUND: kinesin light (beta) chain
BOUND-VIA: binding site
kinesin light (beta) chain (2)
MOTIF: binding site
SITE: khc
EFFECTOR-BOUND: kinesin heavy (alpha) chain
BOUND-VIA: binding site
binding site
FOR-BINDING-OF: protein
References
- Hollenbeck 'News & Views' Nature 347:229 1990
- PROSITE :accession PS00411
Components
kinesin heavy (alpha) chain
kinesin light (beta) chain