BTB/POZ domain-containing protein KCTD3 (renal carcinoma antigen NY-REN-45, KCTD3)

Structure: - contains 1 BTB domain (POZ domain) - contains 5 WD repeats Alternative splicing: namedd isoforms=3 Expression: - broadly expressed in normal tissues Pathology: - reacts with sera from 5-25 % of cancer patients but not with sera from normal donors - 75% of renal cancer patients have antibodies against one or a panel of these antigens

General

BTB/POZ domain containing protein WD repeat protein family

Properties

SIZE: MW = 89 kD entity length = 815 aa MOTIF: BTB domain {18-87} MOTIF: Zinc finger NAME: Zinc finger EFFECTOR-BOUND: Zn+2 WD repeat {224-271} WD repeat {276-313} WD repeat {315-350} WD repeat {419-457} WD repeat {537-577}

Database Correlations

UniProt Q9Y597 Pfam PF02214

References

UniProt :accession Q9Y597