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prosthetic joint

- artificial joint from - total hip arthroplasty - total knee arthroplasty Special laboratory: - arthrocentesis for inflammatory effusion of prosthetic joint to assess for infected prosthesis [4] - a warm, painful, swollen prosthetic joint suggest infected prosthesis if WBC count is > 3000/uL (50,000-100,000 characteristic) with > 75% neutrophils Complications: - 4-6 weeks of therapy with vancomycin or daptomycin for MRSA bacteremia [4] Management: - prophylactic antibiotics (cefazolin or vancomycin) before high-risk procedures in patients with prosthetic joints [1] - treatment of infected joint prostheses without removal of the prosthesis may be successful up to 62% of the time [3] - treat Staphylococcus aureus bacteremia or sepsis with 4-6 weeks of IV antibiotics - IV vancomycin or daptomycin for 4-6 weeks [4]

Interactions

disease interactions

Related

infected prosthesis

Specific

intervertebral biomechanical device wrist prosthesis

General

prosthesis

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 11, 14, American College of Physicians, Philadelphia 1998
  2. Genova A. In: Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 12-15, 2001
  3. Lora-Tamayo J et al. A large multicenter study of methicillin-susceptible and methicillin-resistant Staphylococcus aureus prosthetic joint infections managed with implant retention. Clin Infect Dis 2013 Jan 15; 56:182 PMID: 22942204
  4. NEJM Knowledge+ Rheumatology