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arthralgia

Joint pain. Etiology: 1) arthritis 2) bursitis 3) trauma 4) reaction to medication Epidemiology: - no association with rain [1] Clinical manifestations: - pain with both active & passive range of motion implies intrinsic joint disease [3] - pain with only active range of motion suggests periarticular pathology [3] Laboratory: 1) anti-nuclear antibody (ANA) 2) rheumatoid factor (RF) 3) serum C-reactive protein (serum CRP) 4) erythrocyte sedimentation rate (ESR) 5) serum thyroid-stimulating hormone (serum TSH) Radiology: 1) x-ray of affected joint(s) 2) magnetic resonance imaging as indicated Management: 1) if duration of arthralgias > 3 months, initiate diagnostic workup 2) trial of steroids, prednisone 40 mg PO QD for 6 days 3) return to clinic in one week -> if good response to prednisone & seronegative (ANA, RF), begin hydroxychloroquine (9 month trial) 4) also see arthritis, bursitis

Related

arthritis bursitis

Useful

hydroxychloroquine (Plaquenil) prednisone (Deltasone, Orasone, Liquid Pred, Meticortin, Rayos)

Specific

lower leg joint pain myalgia/arthralgia as part of multisystem disease polyarthralgia

General

musculoskeletal pain

References

  1. Jena AB, Newhouse RL, Olenski AR et al Association between rainfall and diagnoses of joint or back pain: retrospective claims analysis. BMJ 2017;359:j5326 PMID: 29237605 http://www.bmj.com/content/359/bmj.j5326
  2. Schaible HG, von Banchet GS, Boettger MK et al The role of proinflammatory cytokines in the generation and maintenance of joint pain. Ann N Y Acad Sci. 2010 Apr;1193:60-9. PMID: 20398009
  3. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015