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istradefylline (Nourianz)

Indication: - add-on treatment to levodopa/carbidopa in adult patients with Parkinson's disease experiencing 'off' episodes Adverse effects: - dyskinesia, dizziness, constipation, nausea, hallucinations, insomnia Mechanism of action: - adenosine A2A receptor antagonist

General

adenosine A2A receptor antagonist neurologic agent

Database Correlations

PUBCHEM cid=5311037

References

  1. FDA News Release. Aug 27, 2019 FDA approves new add-on drug to treat off episodes in adults with Parkinson's disease. https://www.fda.gov/news-events/press-announcements/fda-approves-new-add-drug-treat-episodes-adults-parkinsons-disease