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isocitrate
Biochemistyr:
- an intermediate metabolite in the citric acid cycle.
- formed from citrate by aconitase-mt
- enzyme: aconitase-mt
- substrate: citrate
- product: isocitrate
- metabolized to alpha-ketoglutarate by isocitrate dehydrogenase in a reaction that feeds electrons into the electron transport chain via NADH
- enzyme: isocitrate dehydrogenase
- substrates: isocitrate + NAD+
- products: alpha-ketoglutarate + NADH + CO2
* see citric acid cycle for role of isocitrate in citric acid cycle
Interactions
molecular events
Related
citric acid cycle, Krebs cycle or tricarboxylic acid [TCA] cycle
General
carboxylate
intermediary metabolite
Database Correlations
PUBCHEM correlations
References
- Wikipedia: Isocitric acid
https://en.wikipedia.org/wiki/Isocitric_acid