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iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2, iron sulfur assembly protein IscA, hIscA, ISCA1, HBLD2, GK004)
Function:
- role in assembly of mitochondrial iron-sulfur proteins
- role in binding of an intermediate of Fe/S cluster assembly
Structure: belongs to the hesB/iscA family
Compartment: mitochondria
Expression:
- detected in cerebellum, kidney, heart
Pathology:
- antibodies against HBLD2 are found in the serum of patients with Sjoegren syndrome, but also in healthy people
General
mitochondrial protein
Properties
SIZE: MW = 14 kD
entity length = 129 aa
COMPARTMENT: mitochondria
Database Correlations
UniProt Q9BUE6
Pfam PF01521
References
UniProt :accession Q9BUE6