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iron-binding acute phase protein (88 kD Eales protein)
removed from 04/17/09 release of UniProt
Function:
- iron binding protein
- inhibits lipid peroxidation in erythrocytes
- may function as an endogenous antioxidant & peroxidase
Structure: glycosylated
Compartment: secreted
Expression:
- found in serum, & in the epiretinal membrane & vitreous humor of the eye
Pathology:
- detected with variable frequency in serum of patients with Eales disease, posterior uveitis, leprosy, tuberculosis & rheumatoid arthritis
- not detected in serum of healthy controls
General
acute phase protein
glycoprotein
metalloprotein
peroxidase
Properties
SIZE: MW = 3 kD
entity length = 28 aa
COMPARTMENT: plasma
MOTIF: metal ion-binding site
active site
MOTIF: heme-binding site
glycosylation site
References
UniProt :accession P83670