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Archaea; Archaebacterium; intestinal methanogen

Epidemiology: - component of intestinal microbiome producing methane (intestinal methanogens) - found in human mouth & skin Biochemistry: - archaea possess genes & metabolic pathways more closely related to those of eukaryotes than bacteria - enzymes involved in transcription & translation - reliance on ether lipids in their cell membranes - archaea use more diverse energy sources than eukaryotes, including sugars, ammonia, metal ions, hydrogen Pathology: - intestinal methanogen overgrowth associated with increased risk & severity of constipation [2]

General

prokaryote

References

  1. Wikipedia: Archaea https://en.wikipedia.org/wiki/Archaea
  2. Mehravar S, Takakura W, Wang J, Pimentel M, Nasser J, Rezaie A. Symptom Profile of Patients With Intestinal Methanogen Overgrowth: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2024 Aug 10:S1542-3565(24)00716-X. PMID: 39147218 Review.