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intensive blood pressure control
Clinical significance:
- unknown
- in the Sprint study, investigators did not come close to achieving target BP
- STEP trial conducted in China with wide target range for systolic BP
- numerous publications would appear to be in conflict with recommendations for intensive blood pressure control in the elderly. See systolic hypertension & blood pressure in the very old.
Clinical trials:
- Sprint study
- STEP trial
Notes:
- meta-analysis [1]
General
antihypertensive therapy
References
- Juraschek SP, Hu JR, Cluett JL et al.
Orthostatic Hypotension, Hypertension Treatment, and Cardiovascular Disease:
An Individual Participant Meta-Analysis.
JAMA. 2023 Oct 17;330(15):1459-1471.
PMID: 37847274 PMCID: PMC10582789 (available on 2024-04-17)
https://jamanetwork.com/journals/jama/fullarticle/2810698