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integrase inhibitor; integrase strand transfer inhibitor (InSTI)
Antiretroviral agents that inhibit or antagonize biosynthesis or actions of integrase.
Indications:
- initial treatment of HIV1 infection [1]
Interactions
drug interactions
drug adverse effects of antiretroviral agents
Related
integrase
Specific
dolutegravir (Tivicay, DTG)
elvitegravir (GS 9137, EVG/c)
raltegravir (Isentress, RAL)
General
antiretroviral agent
enzyme inhibitor
References
- Gunthard HF et al
Antiretroviral Drugs for Treatment and Prevention of HIV Infection
in Adults. 2016 Recommendations of the International Antiviral
Society.
JAMA. 2016;316(2):191-
PMID: 27404187
http://jama.jamanetwork.com/article.aspx?articleid=2533073
- Mayer KH, Krakower DS.
Antiretrovirals for HIV Treatment and Prevention: The Challenges
of Success.
JAMA. 2016 Jul 12;316(2):151-153.
PMID: 27404182
http://jama.jamanetwork.com/article.aspx?articleid=2533044
- Gandhi RT, Bedimo R, Hoy JF et al
Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults.
2022 Recommendations of the International Antiviral Society - USA Panel.
JAMA. Published online December 1, 2022.
PMID: 36454551
https://jamanetwork.com/journals/jama/fullarticle/2799240
- NLM MeSH Browser
http://www.nlm.nih.gov/mesh/meshhome.html