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inositol-3,4,5,6-tetraphosphate (1,3,5,6-IP4)

Inositol-3,4,5,6-tetraphosphate interconversion with inositol- 1,3,4,5,6-pentaphosphate is induced by phospholipase-C (PLC). inhibitor of plasma membrane Ca+2-activated Cl- channels Phosphorylated by ITPK1 to form inositol-1,3,4,5,6-pentaphosphate which is inactive towards Ca+2-activated Cl- channels.

Interactions

molecular events

General

inositol phosphate

Properties

COMPARTMENT: cytoplasm PHOSPHORYLATION: 4-OH

References

  1. Menniti FS, Oliver KG, Putney JW Jr, Shears SB. Inositol phosphates and cell signaling: new views of InsP5 and InsP6. Trends Biochem Sci. 1993 Feb;18(2):53-6. Review. PMID: 8387704
  2. UniProt :accession Q13572