INO80 complex

Function: - chromatin remodeling complex - role in transcriptional regulation, DNA replication & probably DNA repair - complex may dissociate in mitotic cells [2] Structure: - subunits: ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D & INO80E

Properties

COMPARTMENT: cell nucleus SUBUNITS: actin-like protein 6A COMPARTMENT: cell nucleus MOTIF: acetylation site SITE: N-TERMINUS EFFECTOR-BOUND: acetyl Ser phosphorylation site {S233} actin-related protein 5 COMPARTMENT: cytoplasm MOTIF: coiled coil {288-327} coiled coil {355-384} actin-related protein 8 COMPARTMENT: cytoplasm MOTIF: Ser phosphorylation site {S132} Ser phosphorylation site {S412} RVBL1 RVBL2 INO80 complex zinc finger HIT domain-containing protein 4 COMPARTMENT: cell nucleus MOTIF: lysine-rich region {24-37} MOTIF: lysine residue (SEVERAL) glutamate-rich region {132-136} MOTIF: glutamate residue (SEVERAL) coiled coil {200-232} Zinc finger NAME: Zinc finger SITE: 292-323 EFFECTOR-BOUND: Zn+2 protein C18orf37 protein FLJ20309 FORM: protein FLJ20309 Coiled-coil domain-containing protein 95 MOTIF: coiled coil

Components

actin-like protein 6A; 53 kD BRG1-associated factor A; actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit K (ACTL6A, BAF53, BAF53A, INO80K) actin-related protein 5; hARP5; sarcoma antigen NY-SAR-16 (ACTR5, ARP5) actin-related protein 8; INO80 complex subunit N (ACTR8, INO80N) Coiled-coil domain-containing protein 95 (CCDC95. INO80E) protein C18orf37 (INO80C) protein FLJ20309 (INO80D) zinc finger HIT domain-containing protein 4; PAP-1-associated protein 1; PAPA-1; high mobility group AT-hook 1-like 4 (ZNHIT4, INO80B, HMGA1L4, PAPA1)