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initiator element (INR)
Two promoter elements, the TATA box & the initiator element (INR) are capable of directing specific transcription initiation. Most promoters associated with genes transcribed by RNA polymerases II & III contain an initiator element. The initiator element encompasses the transcriptional start site.
Related
general transcription factor II-I; GTFII-I; TFII-I; Bruton tyrosine kinase-associated protein 135; BAP-135; BTK-associated protein 135; SRF-phox1-interacting protein; SPIN; Williams-Beuren syndrome chromosomal region 6 protein (GTF2I, BAP135, WBSCR6)
General
transcriptional start site
promoter element
Properties
FOR-BINDING-OF: general transcription factor II-I
MISC-INFO: LENGTH 17 BP
References
- Weis L, Reinberg D.
Transcription by RNA polymerase II: initiator-directed
formation of transcription-competent complexes.
FASEB J. 1992 Nov;6(14):3300-9. Review.
PMID: 1426767