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importin complex (NLS-binding protein)

Function: - essential for step 1 of nuclear protein transport into the nucleus: binding to the nuclear envelope.

Related

exportin

General

adenosine triphosphatase (ATPase) carrier protein (transporter) multisubunit protein

Properties

MOTIF: active site MOTIF: adenine nucleotide-binding site SUBUNITS: importin alpha subunit MOTIF: binding site FOR-BINDING-OF: nuclear protein FOR-BINDING-VIA: nuclear translocation signal importin beta subunit MOTIF: binding site FOR-BINDING-OF: nuclear membrane

References

  1. Vandromme M et al Regulation of transcription factor localization: fine-tuning of gene expression. Trends Biochem Sci. 1996 Feb;21(2):59-64. Review. PMID: 8851662

Components

importin alpha subunit importin beta subunit