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immunoglobulin light chains.free in serum
Indications:
- evaluation of paraproteinemia, multiple myeloma
Clinical significance:
- most sensitive test for monoclonal gammopathy [1]
- can detect monoclonal light chains before they are detectable with urine protein electrophoresis
Related
Ig light chains (free) panel in serum
Specific
Ig kappa, free in serum
Ig lambda, free in serum
General
immunoglobulin light chains in serum
References
- Medical Knowledge Self Assessment Program (MKSAP) 17, 18.
American College of Physicians, Philadelphia 2015, 18
- Geriatric Review Syllabus, 10th edition (GRS10)
Harper GM, Lyons WL, Potter JF (eds)
American Geriatrics Society, 2019
- Jenner E.
Serum free light chains in clinical laboratory diagnostics.
Clin Chim Acta. 2014 Jan 1;427:15-20. Review.
PMID: 23999048 Free Article