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interleukin-18; IL-18; Iboctadekin; interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma (IL18, IGIF, IL1F4)
Function:
1) augments natural killer cell activity in spleen cells
2) stimulates interferon gamma production in Th1 cells
Structure: belongs to the IL-1 family
Compartment: secreted
Related
interleukin 18 in serum/plasma
interleukin-1 family member
interleukin-18-binding protein; IL-18BP; Tadekinig-alfa (IL18BP)
General
interleukin
Properties
SIZE: entity length = 193 aa
MW = 22 kD
COMPARTMENT: extracellular compartment
Database Correlations
OMIM 600953
UniProt Q14116
Pfam PF00340
Entrez Gene 3606
Kegg hsa:3606
References
- Entrez Gene :accession 3606
- UniProt :accession Q14116
- Wikipedia; Note: interleukin-1 entry
http://en.wikipedia.org/wiki/interleukin_1