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interleukin-20 receptor beta (IL20RB)
Function:
1) IL20RA/IL20RB dimer is a receptor for IL19, IL20 & IL24
2) IL22RA1/IL20RB dimer is a receptor for IL20 & IL24
3) heterodimer with IL20RA & heterodimer with IL22RA1
Structure:
- belongs to the type II cytokine receptor family
- contains 2 fibronectin F3 modules
Compartment: membrane
Expression:
- widely expressed with highest levels in skin & testis
Pathology: highly expressed in psoriatic skin.
Related
psoriasis
General
membrane protein
protein subunit
Properties
SIZE: MW = 35 kD
entity length = 311 aa
MOTIF: signal sequence {1-29}
fibronectin type III domain or F3 module {36-137}
MOTIF: N-glycosylation site {N40}
N-glycosylation site {N134}
fibronectin type III domain or F3 module {144-228}
MOTIF: cysteine residue {C202}
MODIFICATION: cysteine residue {C223}
cysteine residue {C223}
MODIFICATION: cysteine residue {C202}
transmembrane domain {234-254}
Database Correlations
OMIM 605621
UniProt Q6UXL0
Pfam PF00041
Entrez Gene 53833
Kegg hsa:5383
References
- Entrez Gene :accession 53833
- UniProt :accession Q6UXL0
Component-of
interleukin-20 receptor (IL20R, IL19R, IL24R)